COMPARING COVID-19 METAPHORS IN CHINESE AND ENGLISH SOCIAL MEDIA WITH CRITICAL METAPHOR ANALYSIS


Group sequential design for time-to-event outcome with non-proportional hazards using the concept of relative time utilizing two different Weibull distributions

A group sequential design allows investigators to sequentially monitor efficacy and safety as part of interim testing in phase III trials.Literature is well developed in the case of continuous and binary outcomes, however, in case of trials with a time-to-event outcome, popular methods of sample size calculation often assume proportional hazards.In

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A new kymogram-based method reveals unexpected effects of marker protein expression and spatial anisotropy of cytoskeletal dynamics in plant cell cortex

Abstract Background Cytoskeleton can be observed in live plant cells in situ with high spatial and temporal resolution using a combination of specific fluorescent protein tag expression and advanced microscopy methods such as spinning disc confocal microscopy (SDCM) or variable angle epifluorescence microscopy (VAEM).Existing methods for quantifyin

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